Document Detail


Effects of Mullerian anomalies on in vitro fertilization outcome.
MedLine Citation:
PMID:  11699126     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To assess the effect of Mullerian anomalies on pregnancy rates in women undergoing in vitro fertilization (IVF).
METHODS: The records of 37 patients with and 819 patients without Mullerian anomalies undergoing a first cycle of IVF between December 1995 and July 1998 were included in this retrospective study. Outcome variables included maximal estradiol level, number of days of stimulation, number of follicles, number of oocytes, fertilization rate, and ongoing/livebirth pregnancy rate.
RESULTS: Patients with Mullerian anomalies had a significantly lower ongoing pregnancy rate (8.3%) than did controls (24.8%). No patients with diethylstilbestrol (DES)-related anomalies had an ongoing pregnancy.
CONCLUSIONS: Among women with Mullerian anomalies, those with DES exposure in utero demonstrated the poorest outcome.
Authors:
K I Attia; M Hug-Koronya; E S Ginsburg; M D Hornstein
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of assisted reproduction and genetics     Volume:  18     ISSN:  1058-0468     ISO Abbreviation:  J. Assist. Reprod. Genet.     Publication Date:  2001 Oct 
Date Detail:
Created Date:  2001-11-08     Completed Date:  2002-04-12     Revised Date:  2013-02-19    
Medline Journal Info:
Nlm Unique ID:  9206495     Medline TA:  J Assist Reprod Genet     Country:  United States    
Other Details:
Languages:  eng     Pagination:  544-7     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Diethylstilbestrol / adverse effects*
Estradiol / blood
Female
Fertilization in Vitro*
Humans
Male
Mullerian Ducts / abnormalities*,  pathology
Oocytes / physiology
Ovarian Follicle / physiology
Ovulation Induction
Pregnancy
Retrospective Studies
Chemical
Reg. No./Substance:
50-28-2/Estradiol; 56-53-1/Diethylstilbestrol
Comments/Corrections

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