Document Detail


Effects of Melatonin and Epithalamin on the Content of Protein and Lipid Peroxidation Products in Rat Cortex and Hippocampus under Conditions of Acute Hypoxia.
MedLine Citation:
PMID:  23330089     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The effects of melatonin and epithalamin on the content of protein and lipid peroxidation products in the cortex and hippocampus of hypoxic rats were studied under conditions of acute hypobaric hypoxia equivalent to the altitude of 12,000 m. Pineal preparations reduced the intensity of free-radical processes in the brain exposed to acute hypoxia. Epithalamin more effectively than exogenous melatonin protected hippocampal neurons during acute hypoxia by reducing free-radical damage to lipids and proteins.
Authors:
I I Zamorskii; I Yu Sopova; V Kh Khavinson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Bulletin of experimental biology and medicine     Volume:  154     ISSN:  1573-8221     ISO Abbreviation:  Bull. Exp. Biol. Med.     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2013-01-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372557     Medline TA:  Bull Exp Biol Med     Country:  United States    
Other Details:
Languages:  eng; rus     Pagination:  51-3     Citation Subset:  IM    
Affiliation:
Bukovinian State Medical University, Chernovtsy, Ukraine; St. Petersburg Institute of Bioregulation and Gerontology, NorthWestern Division of the Russian Academy of Medical Sciences, Russia. zamorskii@mail.ru.
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