| Effects of Left Ventricular Function on the Exercise Capacity in Patients with Repaired Tetralogy of Fallot. | |
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MedLine Citation:
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PMID: 21929568 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Background: Tissue Doppler imaging has been recently used to evaluate ventricular function. Peak oxygen uptake (V(•) O(2) peak) has been demonstrated as a predictor for death in adults with repaired tetralogy of Fallot (TOF). The aim of this study was to determine which Doppler parameters correlated with V(•) O(2) peak in patients with repaired TOF. Method and Results: Doppler echocardiography, tissue Doppler imaging, and exercise test were performed in 30 patients with TOF after surgical repair. In 30 patients with repaired TOF (median age 14 years, range 9-25 years), 11 patients (37%) were female. Seven patients (median age 12 years) had normal left ventricular diastolic function, whereas the rest of the patients were classified as diastolic dysfunction grade II (median age 15 years; n = 15) and III and IV (median age 18 years; n = 8). The oxygen uptake at anaerobic threshold (V(•) O(2AT) ) and peak exercise in patients with left ventricular diastolic dysfunction was significantly lower than that in those with normal diastolic function. Also, V(•) O(2AT) and V(•) O(2) peak in patients with diastolic dysfunction grade III and IV were significantly lower than that in those with diastolic dysfunction grade II. Left ventricular early diastolic myocardial velocity was most closely correlated to V(•) O(2) peak (r = 0.51; P = 0.005). Peak early ventricular filling velocity to early diastolic myocardial velocity ratio was significantly correlated with V(•) O(2) peak (r =-0.50; P = 0.006). Conclusion: Left ventricular diastolic dysfunction is correlated with V(•) O(2) peak. Left ventricular diastolic function should be a routine echocardiographic assessment in patients with repaired TOF. (Echocardiography, ****;**:1-6). |
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Authors:
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Suchaya Silvilairat; Jatuporn Wongsathikun; Rekwan Sittiwangkul; Yupada Pongprot; Nipon Chattipakorn |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-9-19 |
Journal Detail:
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Title: Echocardiography (Mount Kisco, N.Y.) Volume: - ISSN: 1540-8175 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-9-20 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8511187 Medline TA: Echocardiography Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2011, Wiley Periodicals, Inc. |
Affiliation:
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Department of Pediatrics, Faculty of Medicine Department of Physical Therapy, Faculty of Associated Medical Sciences Cardiac Electrophysiology Research and Training Center, Chiang Mai University, Chiang Mai, Thailand. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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