Document Detail


Effects of Kampo formulations (Chinese herbal medicine traditionally used in Japan) on event-related electric potentials.
MedLine Citation:
PMID:  10579241     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Contingent negative variation (CNV) is a brain function test of the central nervous system in reference to attention, will preparation and motivation. We compared the neuropharmacological effects of 6 main Kampo formulations (1. Mao-to: MA HUANG TANG; 2. Shimbu-to: ZHEN WU TANG; 3. Ninjin-to: REN SHEN TANG; 4. Shigyaku-san: SI NI SAN; 5. Keishi-to: GUI ZHI TANG; and 6. Shimotsu-to: SI WU TANG) on CNV. Mao-to induced significant decrease of CNV in 90 minutes after oral administration. Shimbu-to showed a tendency to increase CNV in 90 minutes after oral administration. Shimotsu-to also induced a transient tendency to increase CNV in 60 minutes after oral administration. Keishi-to showed a decrease of CNV in the early stage of the experiment, while Ninjin-to and Shigyaku-san showed no changes of CNV. From these, it may be concluded that Mao-to and Keishi-to induce sedation of brain function, but Shimbu-to and Shimotsu-to show activation, while Ninjin-to and Shigyaku-san show no changes of brain function regarding CNV related brain function. Furthermore, the time courses of CNV changes were different within the same group (sedation or activation) of Kampo formulations.
Authors:
F H Xu; K Uebaba; J C Cyong
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acupuncture & electro-therapeutics research     Volume:  24     ISSN:  0360-1293     ISO Abbreviation:  Acupunct Electrother Res     Publication Date:  1999  
Date Detail:
Created Date:  1999-12-13     Completed Date:  1999-12-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7610364     Medline TA:  Acupunct Electrother Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  89-104     Citation Subset:  IM    
Affiliation:
International Traditional Medicine Research Center of the Toyama Prefecture International Health Complex, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Attention / physiology
Cerebral Cortex / physiology
Electric Stimulation
Evoked Potentials / drug effects*
Humans
Japan
Male
Medicine, Chinese Traditional
Medicine, Kampo*
Motivation
Plants, Medicinal*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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