Document Detail


Effects of immediate telephone follow-up with providers on sweat chloride test timing after cystic fibrosis newborn screening identifies a single mutation.
MedLine Citation:
PMID:  23102590     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To assess whether reporting "possible cystic fibrosis (CF)" newborn screening (NBS) results via fax plus simultaneous telephone contact with primary care providers (PCPs) versus fax alone influenced 3 outcomes: undergoing a sweat chloride test, age at sweat chloride testing, and undergoing sweat testing before age 8 weeks.
STUDY DESIGN: This was a retrospective cohort comparison of infants born in Wisconsin whose PCP received a telephone intervention (n = 301) versus recent historical controls whose PCP did not (n = 355). Intervention data were collected during a longitudinal research and quality improvement effort; deidentified comparison data were constructed from auxiliary NBS tracking information. Parametric and nonparametric statistical analyses were performed for group differences.
RESULTS: Most infants (92%) with "possible CF" NBS results whose PCP lacked telephone intervention ultimately underwent sweat testing, underlining efficacy for fax-only reporting. Telephone intervention was significantly associated with improvements in the infants undergoing sweat testing at age ≤6 weeks and <8 weeks and a slight, statistically nonsignificant 3.5-day reduction in the infants' age at sweat testing. The effect of telephone intervention was greater for PCPs whose patients underwent sweat testing at community-affiliated medical centers versus those whose patients did so at academic medical centers (P = .008).
CONCLUSION: Reporting "possible CF" NBS results via fax plus simultaneous telephone follow-up with PCPs increases the rate of sweat chloride testing before 8 weeks of age, when affected infants are more likely to receive full benefits of early diagnosis and treatment.
Authors:
Alison La Pean; Michael H Farrell; Kerry L Eskra; Philip M Farrell
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, N.I.H., Extramural     Date:  2012-10-24
Journal Detail:
Title:  The Journal of pediatrics     Volume:  162     ISSN:  1097-6833     ISO Abbreviation:  J. Pediatr.     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-02-26     Completed Date:  2013-04-26     Revised Date:  2013-07-11    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  522-9     Citation Subset:  AIM; IM    
Copyright Information:
Copyright © 2013 Mosby, Inc. All rights reserved.
Affiliation:
Center for Patient Care and Outcomes Research, Medical College of Wisconsin, Milwaukee, WI.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Chlorides / analysis*
Cohort Studies
Cystic Fibrosis / diagnosis*,  genetics
Female
Health Communication / methods*
Humans
Infant
Infant, Newborn
Male
Mutation
Neonatal Screening / methods*
Physician-Patient Relations*
Physicians, Primary Care
Research Design / statistics & numerical data*
Retrospective Studies
Sweat / chemistry*
Telefacsimile
Telephone
Wisconsin
Grant Support
ID/Acronym/Agency:
K01 HL072530/HL/NHLBI NIH HHS; K01-HL072530/HL/NHLBI NIH HHS; R01-HL086691/HL/NHLBI NIH HHS
Chemical
Reg. No./Substance:
0/Chlorides
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Continuous Renal Replacement Therapy for Children ?10 kg: A Report from the Prospective Pediatric Co...
Next Document:  Inflammation or infection at the time of second trimester induced abortion.