| Effects of Ficus carica paste on constipation induced by a high-protein feed and movement restriction in beagles. | |
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MedLine Citation:
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PMID: 22232635 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Constipation is one of the most common functional digestive complaints worldwide. We investigated the laxative effects of figs (Ficus carica L) in a beagle model of constipation induced by high protein diet and movement restriction. The experiments were consecutively conducted over 9 weeks divided into 3 periods of 3 weeks each. All 15 beagles were subjected to a non-treatment (control) period, a constipation induction period, and a fig paste treatment period. We administered fig paste (12 g/kg daily, by gavage) for 3 weeks following a 3-week period of constipation induction in dogs. Segmental colonic transit time (CTT) was measured by counting radiopaque markers (Kolomark) using a radiograph performed every 6 h after feeding Kolomark capsules, until capsules were no longer observed. Fig paste significantly increased fecal quantity in constipated dogs, and segmental CTT was also reduced following fig paste administration. There were no significant differences in feed intake, water intake, body weight, or blood test results, between the constipation and fig paste administration periods. Our results demonstrate that fig is an effective treatment for constipation in beagles. Specifically, stool weight increased and segmental CTT decreased. Fig pastes may be useful as a complementary medicine in humans suffering from chronic constipation. |
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Authors:
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Hong-Geun Oh; Hak-Yong Lee; Min-Young Seo; Young-Rye Kang; Jung-Hoon Kim; Jung-Woo Park; Ok-Jin Kim; Hyang-Im Back; Sun-Young Kim; Mi-Ra Oh; Soo-Hyun Park; Min-Gul Kim; Ji-Young Jeon; Min-Ho Hwang; Sook-Jeong Shin; Soo-Wan Chae |
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Publication Detail:
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Type: Journal Article Date: 2011-12-19 |
Journal Detail:
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Title: Laboratory animal research Volume: 27 ISSN: 2233-7660 ISO Abbreviation: Lab Anim Res Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2012-01-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101560684 Medline TA: Lab Anim Res Country: Korea (South) |
Other Details:
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Languages: eng Pagination: 275-81 Citation Subset: - |
Affiliation:
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Huvet Co., Ltd, Iksan, Korea. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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