Document Detail

Effects of the Er,Cr:YSGG laser on bone and soft tissue in a rat model.
MedLine Citation:
PMID:  21544653     Owner:  NLM     Status:  Publisher    
The purpose of this study was to investigate the histological changes that occur in rat soft and hard tissues after Er,Cr:YSGG laser surgery. Each of 20 rats was submitted to four procedures which were randomly distributed to the right and left sides of the animal: procedure 1 dorsal incision with a scalpel; procedure 2 dorsal incision with a 2.0-W Er,Cr:YSGG laser; procedure 3 skull defect created with a diamond bur; procedure 4 skull defect created with a 3.0-W Er,Cr:YSGG laser. The animals were killed 3, 7, 15 and 30 days after surgery, and histological examinations were performed. The histometric analysis of the bone defects was evaluated using an unpaired t-test. Initially, the dorsum showed more histological signs of repair following procedure 1, although similar healing responses following procedures 1 and 2 were seen on day 30 after surgery. By day 30 the bone formation observed following procedure 4 was much more evident than following procedure 3. The unpaired t-test identified significant differences in bone formation on day 30 (p = 0.01), whereas a greater bone percentage was seen following procedure 4 than following procedure 3 (79.96 ± 10.30% and 58.23 ± 9.99%, respectively). Thus, histological repair of the Er,Cr:YSGG laser wounds was similar to that of the scalpel wounds. However, skull defects created with the Er,Cr:YSGG laser showed greater bone formation than defects created with the bur. Within the limitations of this study, we can conclude that the Er,Cr:YSGG laser is a promising surgical instrument in vivo, particularly for bone surgery.
Livia Rodrigues Perussi; Chaine Pavone; Guilherme José Pimentel Lopes de Oliveira; Paulo Sérgio Cerri; Rosemary Adriana Chierici Marcantonio
Related Documents :
17540753 - Crescent fracture-dislocation of the sacroiliac joint: a functional classification.
21544653 - Effects of the er,cr:ysgg laser on bone and soft tissue in a rat model.
19404943 - Prevention of glucocorticoid-induced bone loss in mice by inhibition of rankl.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-5-5
Journal Detail:
Title:  Lasers in medical science     Volume:  -     ISSN:  1435-604X     ISO Abbreviation:  -     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-5-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8611515     Medline TA:  Lasers Med Sci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Araraquara Dental School, São Paulo State University "Júlio de Mesquita Filho", Araraquara, São Paulo, Brazil.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Predictors for spontaneous stone passage in patients with renal colic secondary to ureteral calculi.
Next Document:  Features and applications of bacterial sialidases.