| Effects of different doses of physical activity on C-reactive protein among women. | |
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MedLine Citation:
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PMID: 19952829 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: The purpose of this study was to examine the influence an exercise training program on CRP in postmenopausal women. METHODS: Sedentary, overweight, or obese postmenopausal women with elevated systolic blood pressure (120-160 mm Hg; n = 464) were randomized into one of four groups: a nonexercise control or one of three aerobic exercise groups; exercise energy expenditure of 4, 8, or 12 kcal·kg(-1)·wk(-1) (KKW) for 6 months at a training intensity of 50% of peak VO2. RESULTS: Complete data for 421 participants were available, and mean (SD) baseline CRP was 5.7 (5.5) mg·L(-1), with no significant differences across groups. Although VO2 increased in a dose-response manner, there were no significant changes in CRP in any of the exercise intervention groups compared with the control group. Change in fitness was not associated with change in CRP, whereas change in weight was significantly associated with change in CRP. CONCLUSIONS: Despite increasing fitness, 6 months of aerobic exercise training did not improve CRP. However, improvements in CRP were associated with reductions in weight. |
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Authors:
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Laura K Stewart; Conrad P Earnest; Steven N Blair; Timothy S Church |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural |
Journal Detail:
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Title: Medicine and science in sports and exercise Volume: 42 ISSN: 1530-0315 ISO Abbreviation: Med Sci Sports Exerc Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-11-25 Completed Date: 2011-04-07 Revised Date: 2011-07-27 |
Medline Journal Info:
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Nlm Unique ID: 8005433 Medline TA: Med Sci Sports Exerc Country: United States |
Other Details:
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Languages: eng Pagination: 701-7 Citation Subset: IM; S |
Affiliation:
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The Cooper Institute. |
| Data Bank Information | |
Bank Name/Acc. No.:
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ClinicalTrials.gov/NCT00011193 |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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C-Reactive Protein
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analysis* Exercise / physiology* Female Humans Middle Aged Obesity / metabolism Overweight / metabolism Oxygen Consumption / physiology Physical Fitness Postmenopause Sedentary Lifestyle Weight Loss |
| Grant Support | |
ID/Acronym/Agency:
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HL071900/HL/NHLBI NIH HHS; HL66262/HL/NHLBI NIH HHS; R01 HL066262-01/HL/NHLBI NIH HHS; R01 HL071900-01/HL/NHLBI NIH HHS; R01 HL071900-02/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
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9007-41-4/C-Reactive Protein |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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