Document Detail

Effects of Different Carbon Sources on the Growth, Fatty Acids Production, and Expression of Three Desaturase Genes of Mortierella alpina ATCC 16266.
MedLine Citation:
PMID:  21365447     Owner:  NLM     Status:  Publisher    
On the molecular and biochemical levels, the effects of different carbon sources on biomass production, fatty acid biosynthesis, and gene expression of three desaturases were investigated in Mortierella alpina ATCC 16266, at a stationary phase, which is an important filamentous fungus capable of producing various polyunsaturated fatty acids (PUFAs). The maximum mycelial biomass was achieved using sucrose as carbon source. However, the highest productivity of total lipids was shown to be no biomass associated. In addition, glucose was the preferred carbon source for the expression of three desaturase genes compared to others, but the change at the corresponding fatty acid product's level of these desaturase genes was not in accordance with the change measured at the mRNA level among those carbon sources that we utilized. Significant discrepancies between the mRNA expression and the product abundance may indicate post-transcriptional regulatory mechanisms of these desaturases.
Ai-Qun Yu; Jian-Chun Zhu; Biao Zhang; Lai-Jun Xing; Mingchun Li
Related Documents :
25049787 - The effect of slaughter season on the fatty acid profile in four types of fat deposits ...
25434877 - The sensitivity and significance analysis of parameters in the model of ph regulation o...
21097597 - Mycolic acid-containing bacteria induce natural-product biosynthesis in streptomyces sp...
18960117 - Kinetics and mechanism of the reaction between biacetyl and hydroxylamine in acid solut...
3570977 - 7-hydro-8-methylpteroylglutamylglutamic acid, a new anti-folate from an actinomycete. f...
23545397 - Formulation of carbenoxolone for delivery to the skin.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-3-2
Journal Detail:
Title:  Current microbiology     Volume:  -     ISSN:  1432-0991     ISO Abbreviation:  -     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-3-2     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7808448     Medline TA:  Curr Microbiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Key Laboratory of Molecular Microbiology and Technology, Ministry of Education, Department of Microbiology, Nankai University, Tianjin, China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Lactobacillus rhamnosus JCM 2771: Impact on Metabolism of Isoflavonoids in the Fecal Flora from a Ma...
Next Document:  Non-nucleoside reverse transcriptase inhibitors efavirenz and nevirapine inhibit cytochrome C oxidas...