| Effects of Diet on High-Density Lipoprotein Cholesterol. | |
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MedLine Citation:
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PMID: 21901431 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Multiple dietary factors have been shown to increase high-density lipoprotein cholesterol (HDL-C) concentrations, and HDL-C has been inversely associated with coronary heart disease (CHD) risk. Replacement of dietary carbohydrate with polyunsaturated, monounsaturated and saturated fat has been associated with progressively greater increases in HDL-C (7-12%) in addition to other lipid changes. Added sugars, but not high glycemic carbohydrates, have been associated with decreased HDL-C. Alcohol consumption has been associated with increased HDL-C (9.2%) independent of changes in other measured lipids. Modest effects on HDL-C (~4-5%) among other lipid and non-lipid CHD risk factors have also been observed with weight loss by dieting, omega-3 fatty acids, and a Mediterranean diet pattern. The CHD benefit of increasing HDL-C is unclear given the inconsistent evidence from HDL-raising pharmacologic trials. Furthermore, pleiotropic effects of diet preclude attribution of CHD benefit specifically to HDL-C. Investigation into functional or other properties of HDL may lend further insight. |
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Authors:
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Patty W Siri-Tarino |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-9-8 |
Journal Detail:
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Title: Current atherosclerosis reports Volume: - ISSN: 1534-6242 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-9-8 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100897685 Medline TA: Curr Atheroscler Rep Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Atherosclerosis Research, Children's Hospital Oakland Research Institute, 5700 Martin Luther King Junior Way, Oakland, CA, 94609, USA, psiri@chori.org. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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