Document Detail

Effects of Diet and Exercise on Insulin Resistance during Pregnancy.
MedLine Citation:
PMID:  18370754     Owner:  NLM     Status:  In-Data-Review    
Current evidence suggests that both diet and exercise can alter the usual increase in insulin resistance seen in Western societies during mid and late pregnancy. A low-glycemic diet combined with a low-volume exercise regimen during pregnancy decreases the glucose and insulin response to both mixed caloric intake and exercise, and probably lowers both 24-h blood glucose concentrations and the maternal substrate utilization ratio of carbohydrate/fat. The end result is a marked decrease in both maternal weight gain and size at birth. Regular weight-bearing exercise alone lowers markers of insulin resistance and lowers blood glucose concentration during and immediately after exercise during pregnancy. Changes in diet and/or physical activity appear to prevent the onset of gestational diabetes mellitus in at-risk women and may be of value in the treatment of those who develop gestational diabetes.
James F Clapp
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Metabolic syndrome and related disorders     Volume:  4     ISSN:  1557-8518     ISO Abbreviation:  Metab Syndr Relat Disord     Publication Date:  2006  
Date Detail:
Created Date:  2008-03-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101150318     Medline TA:  Metab Syndr Relat Disord     Country:  United States    
Other Details:
Languages:  eng     Pagination:  84-90     Citation Subset:  -    
Departments of Reproductive Biology and Obstetrics and Gynecology and Schwartz Center for Metabolism and Nutrition, MetroHealth Medical Campus of Case Western Reserve University, Cleveland, Ohio; and Department of Obstetrics and Gynecology, University of Vermont College of Medicine, Burlington, Vermont.
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