Document Detail


Effects of DC electric countershock on ventricular function, cation balance and endogenous norepinephrine in the dog heart.
MedLine Citation:
PMID:  4458946     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Effects of DC electric countershock on cardiac function in thoracotomized dogs were evaluated from recordings of ECG, aortic pressure, left ventircular pressure and its first derivative, and coronary sinus flow. Samples of arterial and coronary venous plasma and left ventricular myocardium obtained before and after countershock at times corresponding to post-shock arrhythmias and recovery were analyzed for Mg++, K+ and Ca++, and norepinephrine. At 1 min after countershock, ECG changes included transient cardiac arrhythmias and ST segment alterations, accompanied by depressed ventricular function and decreased myocardial Ca++ concentration. At 5 min postshock, coronary venous Mg++ and K+ concentrations had risen and ventricular function was still depressed. Function recovered within 10-20 min. There was no evidence of consistent loss of endogenous myocardial norepinephrine.
Authors:
S Laniado; N M Buckley; C W Frank; D Kambosos
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cardiology     Volume:  59     ISSN:  0008-6312     ISO Abbreviation:  Cardiology     Publication Date:  1974  
Date Detail:
Created Date:  1975-07-24     Completed Date:  1975-07-24     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  1266406     Medline TA:  Cardiology     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  253-67     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Blood Pressure
Calcium / metabolism
Cations, Divalent
Cations, Monovalent
Dogs
Electric Countershock*
Electrocardiography
Heart / physiology*
Magnesium / metabolism
Myocardium / metabolism
Norepinephrine / metabolism*
Potassium / metabolism
Ventricular Function
Chemical
Reg. No./Substance:
0/Cations, Divalent; 0/Cations, Monovalent; 51-41-2/Norepinephrine; 7439-95-4/Magnesium; 7440-09-7/Potassium; 7440-70-2/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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