| Effects of Circuit Residual Volume Salvage Reinfusion on the Postoperative Clinical Outcome for Pediatric Patients Undergoing Cardiac Surgery. | |
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MedLine Citation:
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PMID: 23239310 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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This study aimed to evaluate the effects of washed cardiopulmonary (CPB) circuit residual blood reinfusion on the postoperative clinical outcome for pediatric patients undergoing cardiac surgery. A total of 309 consecutive Chinese cardiac patients receiving CPB between October 2010 and April 2011 were prospectively analyzed. For 217 patients, CPB circuit residual blood was reinfused after the cell-saving procedure [cell-salvage group (CS)]. The remaining 92 patients were directly transfused with allogenic red blood cells (RBCs) after their operation [control group (CON)]. Assessment included perioperative transfusion of RBCs, postoperative hematocrit (HCT), chest tube drainage during the first 24 h after the operation, intrahospital mortality, respiratory morbidity, and renal dysfunction. The two groups were well matched in terms of demographics, CPB data, and complexity of surgical procedure. The patients in the CS group had a significantly higher HCT level postoperatively (p = 0.018) and a less allogenic RBCs transfusion (p = 0.000). The two groups did not differ in terms of chest tube drainage during the first 24 h postoperatively, intrahospital mortality, or respiratory morbidity. The incidence of serum creatinine (≥2-folds) during the first 72 h after the operation was significantly lower in the CS group (2.3 %) than in the CON group (8.7 %) (p = 0.010). Reinfusion of washed CPB circuit residual blood significantly raised the postoperative HCT level, reduced the allogeneic blood transfusion, decreased the incidence of early postoperative renal dysfunction, and did not increase the chest tube drainage after the operation in pediatric cardiac surgery. |
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Authors:
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Lifen Ye; Ru Lin; Yong Fan; Lijun Yang; Jianling Hu; Qiang Shu |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-12-13 |
Journal Detail:
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Title: Pediatric cardiology Volume: - ISSN: 1432-1971 ISO Abbreviation: Pediatr Cardiol Publication Date: 2012 Dec |
Date Detail:
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Created Date: 2012-12-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8003849 Medline TA: Pediatr Cardiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Thoracic and Cardiovascular Surgery, Children's Hospital, School of Medicine, Zhejiang University, 57 Zhugan Lane, Hangzhou, 310003, China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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