Document Detail

Effects of Carbohydrate Ingestion on Acute Leukocyte, Cortisol and IL-6 Response in High-Intensity Long-Distance Running.
MedLine Citation:
PMID:  24796977     Owner:  NLM     Status:  Publisher    
The purpose of this study was to investigate the effect of ingestion of fluids with different carbohydrate concentrations (0 %, 1.5 % and 7 %) on the acute immune stress responses after high-intensity long-distance running. Continuous 18-20 kilometers run was performed at 75% of maximal oxygen uptake with carbohydrate supplementation (CHO7%, 7% carbohydrate solution) and low-carbohydrate supplementation (lowCHO1.5%, 1.5% carbohydrate solution) in a randomized, double-blind, placebo (PLA) controlled design. Seven recreational runners (four males and three females) completed all three trials. Blood was collected at baseline (PRE) and immediately after the run (POST). The running task induced significant (p<0.05) increases in leukocyte (WBC), neutrophil and interleukin-6 (IL-6) counts in every trial. There was a significant (p<0.05) increase in cortisol with PLA and lowCHO1.5% but not with CHO7%. Increase in total leukocyte and neutrophil concentration was significantly lower with CHO7% compared to PLA (p<0.05). Post-exercise IL-6 levels were significantly elevated when compared to baseline in all conditions (p<0.05). IL-6 concentrations did not differ significantly between trials. LowCHO1.5% sport drink did not significantly differ from PLA in measured variables, which indicated that the amount and rate of carbohydrate ingestion (15 g, 10 g [BULLET OPERATOR] h) in low carbohydrate sport drink was not enough to significantly protect from the stress induced by high-intensity long-distance running whereas, the ingestion of CHO7% (45 g [BULLET OPERATOR] h) blunted the significant cortisol response and significantly decreased the leukocyte response.
Johanna K Stenholm; Vuorimaa Timo; Puurtinen Risto; Hämäläinen Ismo; Antti A Mero
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-5-2
Journal Detail:
Title:  Journal of strength and conditioning research / National Strength & Conditioning Association     Volume:  -     ISSN:  1533-4287     ISO Abbreviation:  J Strength Cond Res     Publication Date:  2014 May 
Date Detail:
Created Date:  2014-5-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9415084     Medline TA:  J Strength Cond Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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