Document Detail


The Effects of BleedArrest on Hemorrhage Control in a Porcine Model.
MedLine Citation:
PMID:  23007934     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The purpose of this study was to examine the effectiveness of the hemostatic agent BleedArrest compared to control. This was a prospective, experimental design employing an established porcine model of uncontrolled hemorrhage. The minimum number of animals (n=10 per group) was used to obtain a statistically valid result. There were no statistically significant differences between the groups (P>.05) indicating that the groups were equivalent on the following parameters: activating clotting time, the subject weights, core body temperatures, amount of one minute hemorrhage, arterial blood pressures, and the amount and percentage of total blood volume. There were significant differences in the amount of hemorrhage (P=.033) between the BleedArrest (mean=72, SD±72 mL) and control (mean=317.30, SD±112.02 mL). BleedArrest is statistically and clinically superior at controlling hemorrhage compared to the standard pressure dressing control group. In conclusion, BleedArrest is an effective hemostatic agent for use in civilian and military trauma management.
Authors:
Brian Gegel; James Burgert; Michael Loughren; Don Johnson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  U.S. Army Medical Department journal     Volume:  -     ISSN:  1524-0436     ISO Abbreviation:  US Army Med Dep J     Publication Date:    2012 Oct-Dec
Date Detail:
Created Date:  2012-09-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9617037     Medline TA:  US Army Med Dep J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  31-5     Citation Subset:  IM    
Affiliation:
Veteran Anesthesia Services, PLLC, San Antonio, TX.
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