| Effects of Beta-Blocker Use on Volume Status in Hemodialysis Patients. | |
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MedLine Citation:
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PMID: 22699805 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Background: Removal and control of excess fluid with dialysis is considered critical for protection against cardiovascular sequelae. Antihypertensive agents including beta-blockers may influence hemodynamics, which may limit fluid removal during hemodialysis (HD). Methods: Fifty chronic HD patients underwent bioimpedance measurement before and after a midweek dialysis session. Data on volume status, blood pressure, antihypertensive medications, and bioimpedance were analyzed. Results: Patients in the high-volume status group used a significantly higher percentage of beta-blockers than patients in the low-volume status group (54.2 vs. 19.2%, respectively, p = 0.01). Multivariable regression revealed that the use of beta-blockers was independently positively associated with fluid overload (p < 0.05). Intradialytic muscle cramping occurred more often in the beta-blocker group than the control group (44.4 vs. 12.5%, respectively, p = 0.02). Conclusions: Our results suggest that the use of beta-blockers was associated with fluid overload in HD patients, and patients being treated with them experienced more intradialytic muscle cramping during dialysis. |
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Authors:
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Shu-Hong Bi; Lori Linke; Jimmy Wu; Li-Tao Cheng; Tao Wang; Suhail Ahmad |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-6-12 |
Journal Detail:
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Title: Blood purification Volume: 33 ISSN: 1421-9735 ISO Abbreviation: - Publication Date: 2012 Jun |
Date Detail:
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Created Date: 2012-6-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8402040 Medline TA: Blood Purif Country: - |
Other Details:
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Languages: ENG Pagination: 311-316 Citation Subset: - |
Copyright Information:
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Copyright © 2012 S. Karger AG, Basel. |
Affiliation:
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Division of Nephrology, Peking University Third Hospital, Beijing, PR China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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