Document Detail


Effects of Antiadhesion preparation on free fibrinogen and fibrin degrading products in abdominal exudates of rabbits postoperatively.
MedLine Citation:
PMID:  15309738     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIM: To observe effects of ACOL on fibrinogen (FIB), fibrin degrading products (FDP) and changes of FIB and FDP concentration in rabbits with intro-abdominal exudates during 7 d after major abdominal surgery. METHODS: Sixty New Zealand rabbits were randomly divided into 4 groups: ACOL group, the control group, DCT group and the normal group. After being modeled, except the normal group, the other 3 groups were treated with different ways for a week; the intro-abdominal exudates of rabbits in the 4 groups were drawn for FIB and FDP measurement once daily during 7 d after major abdominal surgery. RESULTS: FIB and FDP in the intro-abdominal exudates altered in a regular way and ACOL could change the concentration of FIB and FDP in the intra-abdominal exudates after major abdominal surgery. CONCLUSION: ACOL can prevent intestinal adhesion by reducing the concentration of FIB and raising that of FDP in the intro-abdominal exudates after major abdominal surgery.
Authors:
You-Li Wang; Cheng-En Pan; Ping-Lin Yang; Yuan Tian; Shu-Wen Pei; Ming Dong
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  World journal of gastroenterology : WJG     Volume:  10     ISSN:  1007-9327     ISO Abbreviation:  World J. Gastroenterol.     Publication Date:  2004 Sep 
Date Detail:
Created Date:  2004-08-13     Completed Date:  2004-12-16     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  100883448     Medline TA:  World J Gastroenterol     Country:  China    
Other Details:
Languages:  eng     Pagination:  2762-6     Citation Subset:  IM    
Affiliation:
Department of Hepatobiliary Surgery, Xi'an Jiaotong University First Hospital, Xi'an 710061, Shaanxi Providence, China. stage9909@sina.com
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MeSH Terms
Descriptor/Qualifier:
Abdomen / surgery
Animals
Ascitic Fluid / drug effects,  metabolism
Drugs, Chinese Herbal / pharmacology*
Exudates and Transudates / drug effects*,  metabolism
Female
Fibrin / metabolism*
Fibrinogen / metabolism*
Male
Postoperative Complications / drug therapy,  prevention & control
Rabbits
Tissue Adhesions / drug therapy,  prevention & control*
Chemical
Reg. No./Substance:
0/Drugs, Chinese Herbal; 9001-31-4/Fibrin; 9001-32-5/Fibrinogen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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