Document Detail


Effects of a 50 Hz magnetic field on Dictyostelium discoideum (Protista).
MedLine Citation:
PMID:  16715524     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Some studies have demonstrated that a few biological systems are affected by weak, extremely low frequency (ELF) electromagnetic fields (EMFs), lower than 10 mT. However, to date there is scanty evidence of this effect on Protists in the literature. Due to their peculiarity as single-cell eukaryotic organisms, Protists respond directly to environmental stimuli, thus appearing as very suitable experimental systems. Recently, we showed the presence of propionylcholinesterase (PrChE) activity in single-cell amoebae of Dictyostelium discoideum. This enzyme activity was assumed to be involved in cell-cell and cell-environment interactions, as its inhibition affects cell aggregation and differentiation. In this work, we have exposed single-cell amoebae of D. discoideum to an ELF-EMF of about 200 microT, 50 Hz, for 3 h or 24 h at 21 degrees C. A delay in the early phase of the differentiation was observed in 3 h exposed cells, and a significant decrease in the fission rate appeared in 24 h exposed cells. The PrChE activity was significantly lower in 3 h exposed cells than in the controls, whereas 24 h exposed cells exhibited an increase in this enzyme activity. However, such effects appeared to be transient, as the fission rate and PrChE activity values returned to the respective control values after a 24 h stay under standard conditions.
Authors:
Andrea Amaroli; Francesca Trielli; Bruno Bianco; Stefano Giordano; Elsa Moggia; Maria Umberta Delmonte Corrado
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Bioelectromagnetics     Volume:  27     ISSN:  0197-8462     ISO Abbreviation:  Bioelectromagnetics     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-09-18     Completed Date:  2006-10-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8008281     Medline TA:  Bioelectromagnetics     Country:  United States    
Other Details:
Languages:  eng     Pagination:  528-34     Citation Subset:  IM    
Affiliation:
Department for the Study of the Territory and its Resources, University of Genoa, Italy.
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MeSH Terms
Descriptor/Qualifier:
Animals
Cell Aggregation / radiation effects
Cell Differentiation / radiation effects
Cell Division / radiation effects
Cholinesterases / analysis
Dictyostelium / physiology,  radiation effects*
Electromagnetic Fields*
Chemical
Reg. No./Substance:
EC 3.1.1.-/propionylcholinesterase; EC 3.1.1.8/Cholinesterases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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