Document Detail


Effects of 28 days of beta-alanine and creatine monohydrate supplementation on aerobic power, ventilatory and lactate thresholds, and time to exhaustion.
MedLine Citation:
PMID:  16953366     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effect of beta-alanine (beta-Ala) alone or in combination with creatine monohydrate (Cr) on aerobic exercise performance is unknown. The purpose of this study was to examine the effects of 4 weeks of beta-Ala and Cr supplementation on indices of endurance performance. Fifty-five men (24.5 +/- 5.3 yrs) participated in a double-blind, placebo-controlled study and randomly assigned to one of 4 groups; placebo (PL, n = 13), creatine (Cr, n = 12), beta-alanine (beta-Ala, n = 14), or beta-alanine plus creatine (CrBA, n = 16). Prior to and following supplementation, participants performed a graded exercise test on a cycle ergometer to determine VO(2peak), time to exhaustion (TTE), and power output, VO(2), and percent VO(2peak) associated with VT and LT. No significant group effects were found. However, within groups, a significant time effect was observed for CrBa on 5 of the 8 parameters measured. These data suggest that CrBA may potentially enhance endurance performance.
Authors:
R F Zoeller; J R Stout; J A O'kroy; D J Torok; M Mielke
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't     Date:  2006-09-05
Journal Detail:
Title:  Amino acids     Volume:  33     ISSN:  1438-2199     ISO Abbreviation:  Amino Acids     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-09-03     Completed Date:  2008-04-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9200312     Medline TA:  Amino Acids     Country:  Austria    
Other Details:
Languages:  eng     Pagination:  505-10     Citation Subset:  IM    
Affiliation:
Department of Exercise Science and Health Promotion, Florida Atlantic University, Davie, FL, USA. rzoeller@fau.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
Anaerobic Threshold / physiology*
Creatine* / administration & dosage,  chemistry,  pharmacology
Dietary Supplements*
Double-Blind Method
Ergometry
Exercise*
Exercise Test
Humans
Male
Muscle Fatigue*
Oxygen Consumption
Physical Endurance / drug effects*
Placebos
Task Performance and Analysis
beta-Alanine* / administration & dosage,  pharmacology
Chemical
Reg. No./Substance:
0/Placebos; 107-95-9/beta-Alanine; 57-00-1/Creatine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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