| Effects of 28-day isolation (ESA-ISEMSI'90) on blood pressure and blood volume regulating hormones. | |
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MedLine Citation:
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PMID: 8476368 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of this study was to determine what effects social isolation and confinement stress had on the volume regulating hormones. In six healthy male subjects, during a 28-d isolation and confinement study (ESA-ISEMSI'90), hematocrit, blood pressure and resting heart rate, plasma cortisol, renin, aldosterone, arginine vasopressin levels besides the electrolyte (Na+, K+) balance and plasma creatinine were measured. During the confinement, an elevated systolic blood pressure (p < 0.01) was observed together with an increase in MHPG corresponding to an elevated mental work load. The pattern displayed by volume regulating hormones (increased values for renin, aldosterone (p < 0.05) and arginine vasopressin) was not only characteristic of confinement stress but also reflected changes in the water and electrolyte metabolism. The increased creatinine levels seen throughout the study were regarded as consequences of hypohydration, and an enhanced muscular catabolism due to reduced physical activity. A similar pattern of hormone modifications was obtained in a head down tilt of the same duration, indicating that some of the described modifications are probably related to isolation and confinement stress. |
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Authors:
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A Maillet; H C Gunga; G Gauquelin; J O Fortrat; A Hope; L Røcker; K Kirsch; C Gharib |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Aviation, space, and environmental medicine Volume: 64 ISSN: 0095-6562 ISO Abbreviation: Aviat Space Environ Med Publication Date: 1993 Apr |
Date Detail:
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Created Date: 1993-05-14 Completed Date: 1993-05-14 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7501714 Medline TA: Aviat Space Environ Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 287-94 Citation Subset: IM; S |
Affiliation:
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Laboratoire de Physiologie de l'Environnement, Faculté de Médecine Lyon Grange-Blanche, France. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Arginine Vasopressin / secretion Atrial Natriuretic Factor / secretion Blood Pressure / physiology Blood Volume / physiology Catecholamines / secretion Heart Rate / physiology Hematocrit Hormones / secretion* Humans Male Osmolar Concentration Social Isolation* Stress, Psychological / physiopathology* |
| Chemical | |
Reg. No./Substance:
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0/Catecholamines; 0/Hormones; 113-79-1/Arginine Vasopressin; 85637-73-6/Atrial Natriuretic Factor |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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