Document Detail


Effects of 0.2 T static magnetic field on human skin fibroblasts.
MedLine Citation:
PMID:  14585318     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Human skin fibroblasts were exposed to 0.2 T static magnetic field generated by a magnetic resonance tomograph. After 1h exposure, cell morphology was modified in association with a concomitant decrease in the expression of some sugar residues of glycoconjugates. Study of cell proliferation and mitogenic signal transduction showed a decrease of thymidine incorporation and of second messenger formation. However, cell viability, assessed by colony forming assay, was unaffected. These results demonstrate that the static magnetic field generated by routinely used magnetic resonance tomograph induces alterations on human skin fibroblasts.
Authors:
Stefania Pacini; Massimo Gulisano; Benedetta Peruzzi; Eleonora Sgambati; Gherardo Gheri; Silvia Gheri Bryk; Simonetta Vannucchi; Gianni Polli; Marco Ruggiero
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Cancer detection and prevention     Volume:  27     ISSN:  0361-090X     ISO Abbreviation:  Cancer Detect. Prev.     Publication Date:  2003  
Date Detail:
Created Date:  2003-10-30     Completed Date:  2004-08-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7704778     Medline TA:  Cancer Detect Prev     Country:  England    
Other Details:
Languages:  eng     Pagination:  327-32     Citation Subset:  IM    
Affiliation:
Department of Human Anatomy, Histology and Forensic Medicine, University of Firenze, viale Morgagni 85, 50134, Firenze, Italy.
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MeSH Terms
Descriptor/Qualifier:
Cell Division
Cell Line
Cell Survival
Fibroblasts* / metabolism,  ultrastructure
Humans
Lectins / metabolism
Magnetic Resonance Imaging
Magnetics*
N-Acetylneuraminic Acid / metabolism
Second Messenger Systems
Chemical
Reg. No./Substance:
0/Lectins; 131-48-6/N-Acetylneuraminic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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