Document Detail


Effectiveness of skin absorption of tincture of I in blocking radioiodine from the human thyroid gland.
MedLine Citation:
PMID:  2722514     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Topical application of tincture of iodine (I) was found to be effective in blocking the thyroid uptake of orally administered 131I in humans. Abdominal skin application of tincture of I resulted in an approximately 82% reduction in the uptake of 131I by the thyroid gland. The effectiveness varied among individuals and may have depended on the quantity applied and on the application site. In each study group, elevated levels of serum I were observed.
Authors:
K L Miller; P E Coen; W J White; W J Hurst; B E Achey; C M Lang
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Health physics     Volume:  56     ISSN:  0017-9078     ISO Abbreviation:  Health Phys     Publication Date:  1989 Jun 
Date Detail:
Created Date:  1989-07-07     Completed Date:  1989-07-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  2985093R     Medline TA:  Health Phys     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  911-4     Citation Subset:  IM    
Affiliation:
College of Medicine, Pennsylvania State University, Milton S. Hershey Medical Center, Hershey 17033.
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MeSH Terms
Descriptor/Qualifier:
Administration, Cutaneous
Adult
Humans
Iodine / administration & dosage*,  therapeutic use
Iodine Radioisotopes / metabolism*
Male
Middle Aged
Skin Absorption*
Solutions
Thyroid Gland / metabolism*
Chemical
Reg. No./Substance:
0/Iodine Radioisotopes; 0/Solutions; 7553-56-2/Iodine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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