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Effectiveness of pre-surgical infant orthopedic treatment for cleft lip and palate patients: a systematic review and meta-analysis.
MedLine Citation:
PMID:  23020693     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Papadopoulos M. A., Koumpridou E. N., Vakalis M. L., Papageorgiou S. N. Effectiveness of pre-surgical infant orthopedic treatment for cleft lip and palate patients: a systematic review and meta-analysis Orthod Craniofac Res 2012;15:207-236. © 2012 John Wiley & Sons A/S ABSTRACT: The objective of the study was to systematically summarize current evidence on the effectiveness of pre-surgical infant orthopedics (PSIO) in cleft lip and palate (CLP) patients. Electronic and manual searches were conducted, and using specific inclusion and exclusion criteria, data extraction and analysis was performed by two independent investigators. When possible, overall pooled estimates with 95% confidence intervals were obtained using the random-effects model. Twenty-four of 885 original studies met the inclusion criteria and were included in the qualitative synthesis, whereas 10 of them were included in the quantitative synthesis (meta-analysis). Except for the variable M-T-C(5) assessing maxillary arch form, which presented an increase at 48 months of follow-up, all other variables concerning craniofacial and dentoalveolar changes demonstrated no significant differences, indicating that PSIO treatment has no effect on CLP patients. The limited evidence derived from this study does not seem to support the short- or long-term effectiveness of PSIO in CLP patients.
Authors:
M A Papadopoulos; E N Koumpridou; M L Vakalis; S N Papageorgiou
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Publication Detail:
Type:  Journal Article     Date:  2012-08-16
Journal Detail:
Title:  Orthodontics & craniofacial research     Volume:  15     ISSN:  1601-6343     ISO Abbreviation:  Orthod Craniofac Res     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-10-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101144387     Medline TA:  Orthod Craniofac Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  207-36     Citation Subset:  D; IM    
Copyright Information:
© 2012 John Wiley & Sons A/S.
Affiliation:
Moschos A. Papadopoulos, Eleni N. Koumpridou, Michail L. Vakalis, Spyridon N. Papageorgiou, Department of Orthodontics, School of Dentistry, Aristotle University of Thessaloniki, Thessaloniki, Greece.
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