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Effectiveness of onion extract gel on surgical scars in asians.
MedLine Citation:
PMID:  22924037     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Background. Onion extracts have been shown in vitro to accelerate wound healing. Results from clinical studies on surgical scars in Caucasians were disappointing. The aim of this study is to evaluate the effectiveness of onion extract gel in improving the cosmetic and symptoms of surgical scars in Asians. Patients/Methods. Twenty Asians who had new Pfannenstiel's cesarean section scars were recruited in this prospective double-blinded, split-scar study. Each side was randomly assigned treatment with onion extract gel or placebo at 7 days after surgery. The product was applied three times daily for 12 weeks. Subjects were evaluated at baseline and 4th and 12th weeks. Scar redness was assessed by calorimeter, scar height and pliability were assessed by blinded investigators, and scar symptoms and overall cosmetic improvement were assessed by subjects. Results. Sixteen subjects completed the study. A statistically significant difference between two sides of scar in terms of scar height and scar symptoms was found. There was no statistically significant difference in scar redness, scar pliability, and overall cosmetic appearance between two sides. Conclusions. The early use of topical 12% onion extract gel on Pfannenstiel's cesarean section scar in Asians resulted in the improvement of scar height and scar symptoms.
Authors:
Kumutnart Chanprapaph; Somsak Tanrattanakorn; Penpun Wattanakrai; Pranee Wongkitisophon; Vasanop Vachiramon
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Publication Detail:
Type:  Journal Article     Date:  2012-08-08
Journal Detail:
Title:  Dermatology research and practice     Volume:  2012     ISSN:  1687-6113     ISO Abbreviation:  Dermatol Res Pract     Publication Date:  2012  
Date Detail:
Created Date:  2012-08-27     Completed Date:  2012-08-27     Revised Date:  2012-09-27    
Medline Journal Info:
Nlm Unique ID:  101312803     Medline TA:  Dermatol Res Pract     Country:  Egypt    
Other Details:
Languages:  eng     Pagination:  212945     Citation Subset:  -    
Affiliation:
Division of Dermatology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Rajthevi, Bangkok 10400, Thailand.
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