| Effectiveness of nutritional supplements for reducing symptoms in autism-spectrum disorder: a case report. | |
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MedLine Citation:
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PMID: 21417812 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Abstract Objective: This report presents a case of a 9-year-old boy with autism that responded positively to nutritional supplements. Methods: The supplements were dimethylglycine and a combination of a large dose of vitamin B6 (pyridoxal HCl) and magnesium. The Autism Treatment Evaluation Checklist (ATEC) was used for outcome assessment and administered by 2 of his family members both before the nutritional supplements and 5 months into the supplements, thereby referred to as pretest and post-test, respectively. Two (2) assessors independently performed evaluations. The ATEC evaluates four areas: communication, sociability, sensory/cognitive awareness, and behavior. The lower the scores are, the less severe the symptoms are. Results: The ATEC evaluations by 2 independent assessors showed that the changes in total ATEC were from 63 at pretest to 33 at post-test, and from 64 at pretest to 30 at post-test, respectively. These changes represented reductions of 47.6% and 53.1%. A strong inter-rater reliability was demonstrated, with an intraclass correlation coefficient of 0.988. The school teachers also noticed improvements in various areas consistent with the ATEC evaluations. Conclusions: Although the reported findings cannot be generalized, this case report provides useful preliminary evidence to an accumulating body of literature supporting the theory and efficacies of nutritional supplements in autism-spectrum disorders. |
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Authors:
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Rebecca Ruiping Xia |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of alternative and complementary medicine (New York, N.Y.) Volume: 17 ISSN: 1557-7708 ISO Abbreviation: J Altern Complement Med Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-03-22 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9508124 Medline TA: J Altern Complement Med Country: United States |
Other Details:
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Languages: eng Pagination: 271-4 Citation Subset: IM |
Affiliation:
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Department of Physical Therapy, Creighton University , Omaha, NE. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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