Document Detail

Effectiveness of micronic aerosol generators and their aerosol characteristics.
MedLine Citation:
PMID:  3536549     Owner:  NLM     Status:  MEDLINE    
We assessed the effectiveness of various aerosol-generating systems. Taplin's settling method and Venticis generators had a lower efficiency (37.3 +/- 3.8% and 51.8 +/- 9.6%, respectively) than the Syntevent (88.8 +/- 6.9%, p less than 0.001), Cadema (89.8 +/- 9.9%, p less than 0.001) and Mefar (85.3 +/- 19.4%, p less than 0.001) generators. The Mass Median Aerodynamic Diameter of the particles produced by the Mefar nebulizer (2.05 +/- 0.27 micron) was larger than that of any other generators (p less than 0.001). The Syntevent (0.54 +/- 0.09 micron) generator produced smaller particles than the Mefar, Taplin (0.89 +/- 0.10 micron, p less than 0.01) and Venticis (0.79 +/- 0.06 micron, p less than 0.02) generators. Particles produced by the Cadema system (0.69 +/- 0.06 micron) were smaller than those generated by the Taplin system (p less than 0.05). We conclude: that the Syntevent, Mefar and Cadema aerosol generators are more efficient than the others, and that all the generators tested except the Mefar may be used for studies that depend on the peripheral deposition of small particles within the lungs.
T Chinet; M A Collignon; D Dusser; L Barritault; G J Huchon
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  European journal of respiratory diseases     Volume:  69     ISSN:  0106-4339     ISO Abbreviation:  Eur J Respir Dis     Publication Date:  1986 Sep 
Date Detail:
Created Date:  1986-12-22     Completed Date:  1986-12-22     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8006891     Medline TA:  Eur J Respir Dis     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  153-9     Citation Subset:  IM    
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MeSH Terms
Nebulizers and Vaporizers*
Particle Size
Pentetic Acid / diagnostic use
Statistics as Topic
Technetium / diagnostic use
Technetium Tc 99m Pentetate
Grant Support
Reg. No./Substance:
0/Aerosols; 65454-61-7/Technetium Tc 99m Pentetate; 67-43-6/Pentetic Acid; 7440-26-8/Technetium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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