Document Detail

The effectiveness of Proctofoam-HC for treatment of hemorrhoids in late pregnancy.
MedLine Citation:
PMID:  19761640     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Currently no topical anti-hemorrhoidal agents have been studied for effectiveness in pregnancy. This study evaluated the effectiveness of Proctofoam-HC used during the last trimester of pregnancy. METHODS: In this prospective, open-label, observational study, pregnant women prescribed Proctofoam-HC were asked to complete two telephone interview questionnaires. RESULTS: A total of 88 women completed the study. All hemorrhoidal symptoms, including pain, pruritus, swelling, itching, decreased significantly (P < 0.001) and overall well-being improved. The improvement was clinically very significant after correction for potential placebo effect. CONCLUSIONS: Proctofoam-HC appears to provide effective treatment of hemorrhoids in late pregnancy.
Sabina Vohra; Hani Akoury; Paul Bernstein; Thomas R Einarson; Nicholas Pairaudeau; Anna Taddio; Gideon Koren
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstétrique et gynécologie du Canada : JOGC     Volume:  31     ISSN:  1701-2163     ISO Abbreviation:  J Obstet Gynaecol Can     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-09-18     Completed Date:  2009-10-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101126664     Medline TA:  J Obstet Gynaecol Can     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  654-9     Citation Subset:  IM    
The Motherisk Program, Hospital for Sick Children, Toronto, ON, Canada.
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MeSH Terms
Administration, Topical
Anti-Inflammatory Agents / therapeutic use*
Drug Combinations
Hemorrhoids / drug therapy*
Hydrocortisone / therapeutic use*
Morpholines / therapeutic use*
Pregnancy Complications / drug therapy*
Prospective Studies
Reg. No./Substance:
0/Anti-Inflammatory Agents; 0/Drug Combinations; 0/Morpholines; 50-23-7/Hydrocortisone; 78457-00-8/proctofoam-HC

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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