Document Detail


Effectiveness of No-Sting skin protectant and Aquaphor on water loss and skin integrity in premature infants.
MedLine Citation:
PMID:  19890343     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The purpose of this study was to evaluate the effects of No-Sting skin protectant and Aquaphor, a water-based emollient, on skin integrity measured by Neonatal Skin Condition Score (NSCS) and transepidermal water loss (TEWL) in premature infants. In addition, with no data regarding the use of No-Sting in the neonatal population and its desirability because it requires less infant manipulation and less nursing time, it was important to evaluate the use of this product. STUDY DESIGN: In all, 69 premature infants born at <33 weeks gestation were randomly assigned to one of the two treatment groups: (1) No-Sting or (2) Aquaphor for a total of 14 days. RESULT: Gestational age and total fluid intake were related to NSCS whereas gestational age, incubator humidity levels and total daily fluid intake were significantly related to TEWL. Infants receiving Aquaphor had significantly higher NSCS, but the mean scores in both groups over the 14-day period were in the normal range (<4). There were no differences between Aquaphor and No-Sting in the rate of TEWL over the 14-day period. CONCLUSION: This study provides the first information regarding the use of No-Sting in the neonatal population. This skin protectant seems as effective as Aquaphor in decreasing TEWL and maintaining skin integrity, and is less resource intensive.
Authors:
D H Brandon; K Coe; D Hudson-Barr; T Oliver; L R Landerman
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't     Date:  2009-11-05
Journal Detail:
Title:  Journal of perinatology : official journal of the California Perinatal Association     Volume:  30     ISSN:  1476-5543     ISO Abbreviation:  J Perinatol     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-05-28     Completed Date:  2010-09-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8501884     Medline TA:  J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  414-9     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Duke University School of Nursing, Duke University Hospital, Durham, NC 27710, USA. debra.brandon@duke.edu
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MeSH Terms
Descriptor/Qualifier:
Emollients / therapeutic use*
Female
Humans
Infant, Newborn
Infant, Premature / physiology*
Male
Skin Care*
Water Loss, Insensible
Chemical
Reg. No./Substance:
0/Emollients

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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