Document Detail


Effective use of methylprednisolone aceponate 0.1% in a 9-month-old infant with atopic eczema and sleep disturbance.
MedLine Citation:
PMID:  23067433     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
A 9-month-old infant, with no family history of atopy, presenting with erythematous, itchy plaques, and sleep disturbance, was diagnosed with atopic eczema (AE). Previous treatment with topical hydrocortisone and emollients had little effect. The infant was treated nightly with methylprednisolone aceponate (MPA) 0.1% (Advantan(®) ) cream, in addition to emollients and an oral antihistamine. After 1 week of once-daily MPA 0.1% treatment, followed by 1 week of alternate-day treatment with Advantan, significant improvements in AE symptoms and sleep were observed. The patient's caregiver reported overall treatment satisfaction and no side effects of Advantan. For this infant with newly diagnosed AE, Advantan improved symptoms and sleep quality in a safe and well-tolerated manner.
Authors:
S Machado
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the European Academy of Dermatology and Venereology : JEADV     Volume:  26 Suppl 6     ISSN:  1468-3083     ISO Abbreviation:  J Eur Acad Dermatol Venereol     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-10-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9216037     Medline TA:  J Eur Acad Dermatol Venereol     Country:  England    
Other Details:
Languages:  eng     Pagination:  14-5     Citation Subset:  IM    
Copyright Information:
© 2012 The Author. Journal of the European Academy of Dermatology and Venereology © 2012 European Academy of Dermatology and Venereology.
Affiliation:
Department of Dermatology, Hospital de Santo António, Centro Hospitalar do Porto, Porto, Portugal.
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