Document Detail


Effective treatment of gonorrhoea.
MedLine Citation:
PMID:  142006     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Effective therapy of gonorrhoea has changed drastically over the years, reflecting the progessive acquisition of relative antibiotic resistance by the causative organism. Although in the US. th 1974 USPHS recommendations are the best guidelines for management at present, recent epidemiological trends may obviate some of these provisions. The most important of these trends is the emergence of R-factor carrying strains capable of producing penicillinase, thereby making these strains absolutely resistant to clinically achievable levels of penicillin. This review analyses this problem in the context of reasonable therapeutic goals and also discusses optimum management of patients with such complications as pharyngeal infection, pelvic inflammatory disease and disseminated gonococcal infection.
Authors:
B I Eisenstein
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Drugs     Volume:  14     ISSN:  0012-6667     ISO Abbreviation:  Drugs     Publication Date:  1977 Jul 
Date Detail:
Created Date:  1977-09-22     Completed Date:  1977-09-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7600076     Medline TA:  Drugs     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  57-67     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Anti-Bacterial Agents / administration & dosage,  pharmacology,  therapeutic use*
Drug Administration Schedule
Female
Gonorrhea / complications,  drug therapy*,  microbiology
Humans
Kinetics
Male
Pelvic Inflammatory Disease / drug therapy,  etiology
Penicillin Resistance
Penicillins / adverse effects,  metabolism,  therapeutic use
Pharyngeal Diseases / drug therapy
Spectinomycin / therapeutic use
Syphilis / complications,  drug therapy
Urethritis / drug therapy,  etiology
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Penicillins; 1695-77-8/Spectinomycin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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