Document Detail

Effect of xylitol and fluoride on enamel erosion in vitro.
MedLine Citation:
PMID:  18195513     Owner:  NLM     Status:  MEDLINE    
This study aimed to determine the anti-erosive effects of xylitol, fluoride and a xylitol/fluoride combination used as an additive in an acidic drink or as mouthrinse after enamel was exposed to an acidic drink, in vitro. Human third molars were divided into 7 groups (A-G). Samples from groups A to D were immersed for 5 min in orange juice only (A), orange juice plus either 25% xylitol (B), F(-) 1 ppm (C) or a 25% xylitol/F(-) 1 ppm combination (D), respectively. Samples from groups E to G were immersed in orange juice for 5 min and then in either 40% xylitol (E), F(-) 227 ppm (F) or a 40% xylitol/F(-) 227 ppm combination (G), for 1 min respectively. This process was performed four times daily for 14 days. Mineral loss was determined from the lesion depth and surface hardness. Erosion depth progressively increased in all groups, except E, where erosion depth was significantly lower than group A. Surface microhardness progressively decreased in all groups, except E, where hardness was significantly higher than group A. This study demonstrated that addition of xylitol, fluoride or a xylitol/fluoride combination to an acidic drink or post-treatment with fluoride or a xylitol/fluoride combination could reduce, but not prevent, enamel erosion.
Siriwan Chunmuang; Suwanna Jitpukdeebodintra; Chanya Chuenarrom; Pojjanut Benjakul
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of oral science     Volume:  49     ISSN:  1343-4934     ISO Abbreviation:  J Oral Sci     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2008-01-15     Completed Date:  2008-04-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9808942     Medline TA:  J Oral Sci     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  293-7     Citation Subset:  D; IM    
Department of Prosthetic Dentistry, Faculty of Dentistry, Prince of Songkla University, Songkla, Thailand.
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MeSH Terms
Beverages / adverse effects
Cariostatic Agents / therapeutic use*
Citric Acid / adverse effects
Drug Combinations
Fluorides / therapeutic use*
Food Additives
Molar, Third
Mouthwashes / therapeutic use
Tooth Demineralization / etiology
Tooth Erosion / etiology,  prevention & control*
Xylitol / therapeutic use*
Reg. No./Substance:
0/Cariostatic Agents; 0/Drug Combinations; 0/Fluorides; 0/Food Additives; 0/Mouthwashes; 77-92-9/Citric Acid; 87-99-0/Xylitol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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