Document Detail

Effect of vitamin E deficiency on neurologic function in patients with cystic fibrosis.
MedLine Citation:
PMID:  3171788     Owner:  NLM     Status:  MEDLINE    
We evaluated neurologic function in 18 patients, ages 5 to 26 years, with cystic fibrosis. Eight were deficient in vitamin E. Sural nerve conduction latency was increased and nerve action potential amplitude decreased in the vitamin E-deficient group in comparison with the vitamin E-sufficient group. Two vitamin E-deficient patients had absent deep tendon reflexes; findings of clinical neurologic examinations were otherwise normal. We recommend early supplementation with vitamin E for patients with cystic fibrosis who have pancreatic insufficiency, to prevent neurologic dysfunction.
H A Cynamon; D E Milov; E Valenstein; M Wagner
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of pediatrics     Volume:  113     ISSN:  0022-3476     ISO Abbreviation:  J. Pediatr.     Publication Date:  1988 Oct 
Date Detail:
Created Date:  1988-11-10     Completed Date:  1988-11-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  637-40     Citation Subset:  AIM; IM    
Department of Pediatrics, University of Florida, Gainesville 32610.
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MeSH Terms
Action Potentials
Alanine Transaminase / blood
Aspartate Aminotransferases / blood
Bile Acids and Salts / blood
Child, Preschool
Cystic Fibrosis / physiopathology*
Nervous System / physiopathology*
Reflex / physiology
Sural Nerve / physiopathology
Vitamin E Deficiency / physiopathology*
Reg. No./Substance:
0/Bile Acids and Salts; EC Aminotransferases; EC Transaminase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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