| Effect of vitamin B6 supplementation in McArdle's disease: a strategic case study. | |
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MedLine Citation:
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PMID: 9631404 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A patient-blind study into the effect of a 10-week cessation of long-term vitamin B6 supplementation on B6 status and performance in McArdle's disease is reported. Muscle performance was assessed both subjectively and objectively by an ischaemic fatiguing protocol of the adductor pollicis muscle. Nine weeks after withdrawal of supplementation, vitamin B6 status had changed from adequacy to inadequacy and the force loss during the ischaemic fatiguing protocol had increased at all frequencies studied. The patient reported decreased exercise tolerance after 7 weeks and by the tenth week was experiencing an increase in muscle cramps. Vitamin B6 status and muscle performance may be linked in McArdle's disease and there is potential for enhancement of performance by B6 supplementation. |
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Authors:
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J Phoenix; P Hopkins; C Bartram; R J Beynon; R C Quinlivan; R H Edwards |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Neuromuscular disorders : NMD Volume: 8 ISSN: 0960-8966 ISO Abbreviation: Neuromuscul. Disord. Publication Date: 1998 May |
Date Detail:
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Created Date: 1998-08-28 Completed Date: 1998-08-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9111470 Medline TA: Neuromuscul Disord Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 210-2 Citation Subset: IM |
Affiliation:
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Department of Biomolecular Science, UMIST, Manchester, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Dietary Supplements Exercise Glycogen Storage Disease Type V / complications, drug therapy*, physiopathology Humans Male Middle Aged Muscle Cramp / etiology, physiopathology Muscle, Skeletal / physiopathology Physical Endurance / physiology Pyridoxine / administration & dosage, therapeutic use* |
| Chemical | |
Reg. No./Substance:
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65-23-6/Pyridoxine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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