Document Detail

Effect of a vigorous aerobic regimen on physical performance in breast cancer patients - a randomized controlled pilot trial.
MedLine Citation:
PMID:  17453366     Owner:  NLM     Status:  MEDLINE    
This randomized, controlled pilot trial was carried out to assess the feasibility and efficacy of an aerobic exercise in enhancing physical performance of breast cancer patients after adjuvant treatments. The potential of the training regimen to prevent accompanying bone loss was also assessed. Thirty patients, 41-65 years of age, were randomly assigned into training or control groups shortly after adjuvant chemo- or radiotherapy. The 12-week training included a guided aerobic exercise session once a week (the effective part being either step aerobic- or circuit-training in alternate weeks) and similar home exercise sessions twice a week. Adherence to the guided sessions was 78%, while home training was performed an average 2.1 times per week. Agility assessed with figure-8 running test and peak jumping power showed significant between-group treatment-effects (approximately 5% and approximately 10%, respectively). Judged from the accelerometer data, reaction forces up to six times body weight occurred during the training, which implies that the training could also have potential to affect bone mass. The present exercise regimen turned out to be feasible and effective among breast cancer patients in terms of physical performance. Large controlled trials are necessary to confirm these findings.
Riku Nikander; Harri Sievänen; Katriina Ojala; Tiina Oivanen; Pirkko-Liisa Kellokumpu-Lehtinen; Tiina Saarto
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta oncologica (Stockholm, Sweden)     Volume:  46     ISSN:  0284-186X     ISO Abbreviation:  Acta Oncol     Publication Date:  2007  
Date Detail:
Created Date:  2007-04-24     Completed Date:  2007-06-01     Revised Date:  2009-05-12    
Medline Journal Info:
Nlm Unique ID:  8709065     Medline TA:  Acta Oncol     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  181-6     Citation Subset:  IM    
Bone Research Group, UKK Institute for Health Promotion Research, Tampere, Finland.
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MeSH Terms
Bone Resorption / chemically induced,  prevention & control*
Breast Neoplasms / drug therapy,  rehabilitation*
Chemotherapy, Adjuvant / adverse effects
Exercise Therapy / methods*
Middle Aged
Patient Compliance
Physical Fitness*
Pilot Projects

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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