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EFFECT OF THE USE OF PROBIOTICS IN THE TREATMENT OF CHILDREN WITH ATOPIC DERMATITIS; A LITERATURE REVIEW.
MedLine Citation:
PMID:  23808426     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Introduction: Atopic dermatitis (AD) is a disease that mainly affects the pediatric population involving chronic and repetitive inflammatory skin manifestations. Its evolution is known as atopic march, which is characterized by the occurrence of respiratory and food allergies. Aim: To carry out a classical review of the state-of-theart scientific literature regarding the effect of probiotics on the treatment of children with AD. Methods: Searches were conducted in Medline and Lilacs through the portals PubMed (http://www.ncbi.nlm. nih.gov/pubmed/) and SciELO (http://www.scielo.br). There was a selection of the available publications in the period from 2001 to 2011, using the keywords atopic dermatitis and probiotics (in English and in Portuguese). Results: After applying the inclusion and exclusion criterias, we selected 12 case-control studies which were conducted in four European countries and Australia. The methodological quality of the studies was assessed according to the STROBE recommendations. Assessment of agreement among researches in classifying the quality of the articles showed excellent agreement (k = 1.00, 95%) with a total of 9 papers at B level. The majority of the studies (75%) indicated a beneficial biological effect of probiotics on AD, including protection against infections, enhancement of the immune response, inflammation reduction and changes in gut the flora. The remaining studies showed no beneficial effects according to the outcomes of interest. Conclusion: The majority of the studies in the scientific literature in this review showed improvements in some inflammatory parameters and in intestinal microbiota and not exactly, changes in clinical parameters. However, the biological effects observed in most of them suggest the possibility of benefits of the use of probiotics as an adjunvant in the treatment of AD.
Abstract available from the publisher.
Authors:
Ingrid Pillar da Costa Baptista; Elizabeth Accioly; Patricia de Carvalho Padilha
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Nutricion hospitalaria : organo oficial de la Sociedad Espanola de Nutricion Parenteral y Enteral     Volume:  28     ISSN:  1699-5198     ISO Abbreviation:  Nutr Hosp     Publication Date:    2013 Enero-Febrero
Date Detail:
Created Date:  2013-7-1     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9100365     Medline TA:  Nutr Hosp     Country:  -    
Other Details:
Languages:  ENG     Pagination:  16-26     Citation Subset:  -    
Copyright Information:
Copyright © AULA MEDICA EDICIONES 2013. Published by AULA MEDICA. All rights reserved.
Vernacular Title:
EFECTO DEL USO DE LOS PROBIóTICOS EN EL TRATAMIENTO DE NIñOS CON DERMATITIS ATóPICA; REVISIóN BIBLIOGRáFICA.
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