| THE EFFECT OF URETHANE ON THE CONSUMPTION OF OXYGEN AND THE RATE OF CELL DIVISION IN THE CILIATE TETRAHYMENA GELEII. | |
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MedLine Citation:
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PMID: 19873395 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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1. The inhibition of oxygen consumption produced by a series of concentrations of ethyl carbamate has been measured in the protozoan Tetrahymena geleii. 2. The relation found between the narcotic concentration and its effect on respiration leads to the conclusion that urethane has two distinct modes of action in this cell. The respiratory data can be accurately predicted by assuming that the inhibitor acts on two independent parallel respiratory systems. 3. Complete suppression of cell division in this organism is brought about by approximately 0.1 M urethane. 4. Urethane concentrations up to 0.1 M affect primarily only one of the two postulated respiratory systems. The mechanism of the narcosis of cell division in this organism by urethane thus appears to be inhibition of this "activity" system. |
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Authors:
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R A Ormsbee; K C Fisher |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of general physiology Volume: 27 ISSN: 0022-1295 ISO Abbreviation: J. Gen. Physiol. Publication Date: 1944 May |
Date Detail:
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Created Date: 2010-06-23 Completed Date: 2010-06-23 Revised Date: 2010-09-28 |
Medline Journal Info:
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Nlm Unique ID: 2985110R Medline TA: J Gen Physiol Country: United States |
Other Details:
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Languages: eng Pagination: 461-8 Citation Subset: - |
Affiliation:
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Brown University, Providence, Rhode Island, and The Marine Biological Laboratory, Woods Hole, Massachusetts. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
| Full Text | |
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Journal Information Journal ID (nlm-ta): J Gen Physiol ISSN: 0022-1295 ISSN: 1540-7748 Publisher: The Rockefeller University Press |
Article Information Download PDF  Copyright © Copyright, 1944, by The Rockefeller Institute for Medical Research Received Day: 31 Month: 12 Year: 1943 Print publication date: Day: 20 Month: 5 Year: 1944 Volume: 27 Issue: 5 First Page: 461 Last Page: 468 ID: 2238023 PubMed Id: 19873395 |
| THE EFFECT OF URETHANE ON THE CONSUMPTION OF OXYGEN AND THE RATE OF CELL DIVISION IN THE CILIATE TETRAHYMENA GELEII | |
| Richard A. Ormsbee | |
| Kenneth C. Fisher | |
| From Brown University, Providence, Rhode Island, and The Marine Biological Laboratory, Woods Hole, Massachusetts |
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