| Effect of two types of fish oil supplementation on plasma and erythrocyte phospholipids in formula-fed term infants. | |
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MedLine Citation:
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PMID: 9784633 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We studied the effect of docosahexaenoic acid (DHA) supplementation of infant formulas on fatty acid composition of blood phospholipids in term infants. Two fish oil supplemented formulas containing 0.45 wt% DHA and high (0.35%) or low (0.10%) eicosapentaenoic acid (EPA) were fed for 42 days and compared with a standard formula and breast milk. Infants fed supplemented formulas and breast milk had similar time-dependent changes for DHA from birth to day 42, i.e., slight decreases in plasma phospholipids and erythrocyte phosphatidylcholine and no change in erythrocyte phosphatidylethanolamine. Low-EPA formula prevented EPA accumulation but did not limit the significant decrease in arachidonic acid (AA) noted in infants fed high-EPA formula. These results suggest that term infant formulas should be supplemented with DHA-rich EPA, low fish oil and AA to achieve a fatty acid status in formula-fed infants similar to that of breast-fed infants. |
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Authors:
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C Maurage; P Guesnet; M Pinault; J Rochette de Lempdes; G Durand; J Antoine; C Couet |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Biology of the neonate Volume: 74 ISSN: 0006-3126 ISO Abbreviation: Biol. Neonate Publication Date: 1998 Dec |
Date Detail:
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Created Date: 1998-12-18 Completed Date: 1998-12-18 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0247551 Medline TA: Biol Neonate Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 416-29 Citation Subset: IM |
Affiliation:
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Equipe Associée, Université de Tours EA2103-INRA, Laboratoire de Nutrition et Securité Alimentaire, Jouy-en-Josas, France. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Arachidonic Acid
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administration & dosage Dietary Supplements* Docosahexaenoic Acids / administration & dosage Eicosapentaenoic Acid / administration & dosage Erythrocytes / metabolism* Fatty Acids / blood Fatty Acids, Omega-3 / administration & dosage Fish Oils / administration & dosage* Gestational Age Growth Humans Infant Food* Infant, Newborn Phospholipids / blood* Vitamin E / blood |
| Chemical | |
Reg. No./Substance:
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0/Fatty Acids; 0/Fatty Acids, Omega-3; 0/Fish Oils; 0/Phospholipids; 1406-18-4/Vitamin E; 1553-41-9/Eicosapentaenoic Acid; 25167-62-8/Docosahexaenoic Acids; 506-32-1/Arachidonic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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