Document Detail

Effect of tulipin on cell cycle progression analyzed by BrdUrd incorporation.
MedLine Citation:
PMID:  2312349     Owner:  NLM     Status:  MEDLINE    
The effect of tulipin, a protein from plant origin recently purified, on cell cycle progression has been analyzed in the sensitive EUE cells by BrdUrd incorporation. The cytofluorimetric results demonstrate that tulipin specifically interacts with the S phase, with a dose-dependent decrease of the total S phase cells and an increase of the G1/G2 cells after 4 h of treatment in the synchronized EUE cells, whereas in the asynchronous population it mainly causes a dose-dependent decrease in the incorporation of BrdUrd per cell.
M Vitale; S Papa; L Roncuzzi; A Gasperi-Campani
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Histochemistry     Volume:  93     ISSN:  0301-5564     ISO Abbreviation:  Histochemistry     Publication Date:  1990  
Date Detail:
Created Date:  1990-04-23     Completed Date:  1990-04-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0411300     Medline TA:  Histochemistry     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  229-31     Citation Subset:  IM    
Istituto di Anatomia Umana Normale, Università di Bologna, Italia.
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MeSH Terms
Bromodeoxyuridine / metabolism*
Cell Cycle / drug effects*
Dose-Response Relationship, Drug
Flow Cytometry
Plant Proteins / pharmacology*
Tumor Cells, Cultured / cytology
Reg. No./Substance:
0/Glycoproteins; 0/Plant Proteins; 0/tulipin protein, Tulipa; 59-14-3/Bromodeoxyuridine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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