| Effect of training intensity on muscle lactate transporters and lactate threshold of cross-country skiers. | |
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MedLine Citation:
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PMID: 11683677 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The training intensity may affect the monocarboxylate transporters MCT1 and MCT4 in skeletal muscle. Therefore, 20 elite cross-country skiers (11 men and nine women) trained hard for 5 months at either moderate (MIG, 60-70% of VO2max) or high intensity (HIG, 80-90%). The lactate threshold, several performance parameters, and the blood lactate concentration (cLa) after exhausting treadmill running were also determined. Muscle biopsies taken from the vastus lateralis muscle before and after the training period were analysed for the two MCTs and for muscle fibre types and six enzymes. The concentration of MCT1 did not change for HIG (P=0.3) but fell for MIG (-12 +/- 3%, P=0.01); the training response differed between the two groups (P=0.05). The concentration of MCT4 did not change during the training period (P > 0.10). The concentration of the two MCTs did not differ between the two sexes (P=0.9). The running speed at the lactate threshold rose for HIG (+3.2 +/- 0.9%, P=0.003), while no change was seen for MIG (P=0.54); the training response differed between the two groups (P=0.04). The cLa after long-lasting exhausting treadmill running correlated with the concentration of MCT1 (rs=0.69, P=0.002), but not with that of MCT4 (rs=0.2, P=0.2). There were no other significant correlations between the concentrations of the two MCTs and the performance parameters, muscle fibre types, or enzymes (r < or = 0.36, P > 0.10). Thus, the training response differed between MIG and HIG both in terms of performance and of the effect on MCT1. Training at high intensity may be more effective for cross-country skiers. Finally, MCT1 may be important for releasing lactate to the blood during long-lasting exercise. |
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Authors:
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F Evertsen; J I Medbø; A Bonen |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Acta physiologica Scandinavica Volume: 173 ISSN: 0001-6772 ISO Abbreviation: Acta Physiol. Scand. Publication Date: 2001 Oct |
Date Detail:
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Created Date: 2001-10-30 Completed Date: 2002-01-02 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0370362 Medline TA: Acta Physiol Scand Country: England |
Other Details:
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Languages: eng Pagination: 195-205 Citation Subset: IM |
Affiliation:
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Norwegian University of Sport and Physical Education, Ullevå Stadion, Oslo, Norway. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Exercise / physiology* Exercise Test Female Humans Lactic Acid / blood* Male Monocarboxylic Acid Transporters / metabolism* Muscle Fibers, Skeletal / metabolism Muscle Proteins* Muscle, Skeletal / cytology, physiology* Oxygen Consumption / physiology Skiing / physiology* Symporters / metabolism |
| Chemical | |
Reg. No./Substance:
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0/Monocarboxylic Acid Transporters; 0/Muscle Proteins; 0/SLC16A4 protein, human; 0/Symporters; 0/monocarboxylate transport protein 1; 50-21-5/Lactic Acid |
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