| Effect of tracheal and tongue displacement on upper airway airflow dynamics. | |
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MedLine Citation:
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PMID: 8806927 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We have previously shown that caudal tracheal displacement alters the airflow dynamics of the upper airway. In the present study, we specifically examined the effects of tongue and tracheal displacement on upper airway airflow dynamics. To determine how tongue and tracheal displacement modulate maximal inspiratory airflow (VImax), we analyzed the pressure-flow relationships obtained in the isolated upper airway of paralyzed cats. VImax and its determinants, the pharyngeal critical pressure (Pcrit) and the nasal resistance (Rn) upstream to the flow-limiting site, were measured as tongue displacement and tracheal displacement were systematically varied. Four results were obtained: 1) there was no independent effect of tongue displacement on VImax, Pcrit, or Rn; 2) there was an increase in VImax with 2 cm of tracheal displacement, which was associated with a decrease in Pcrit and an increase in Rn; 3) there was an interactive effect of tongue and tracheal displacement on VImax and Pcrit but not on Rn; and 4) there was a large increase in VImax with tongue displacement > 2.5 cm with the trachea nondisplaced, which was associated with a large decrease in Pcrit and a large increase in Rn. We conclude that tongue and tracheal displacement exert differing influences on airflow dynamics and present a mechanical model of the upper airway that explains these results. |
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Authors:
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J A Rowley; S Permutt; S Willey; P L Smith; A R Schwartz |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of applied physiology (Bethesda, Md. : 1985) Volume: 80 ISSN: 8750-7587 ISO Abbreviation: J. Appl. Physiol. Publication Date: 1996 Jun |
Date Detail:
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Created Date: 1996-12-03 Completed Date: 1996-12-03 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 8502536 Medline TA: J Appl Physiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 2171-8 Citation Subset: IM |
Affiliation:
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Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland 21224, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Airway Resistance
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physiology* Animals Cats Male Models, Biological Pressure Pulmonary Ventilation / physiology* Tongue / physiology* Trachea / physiology* |
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