| Effect of topical timolol maleate on exercise performance. | |
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MedLine Citation:
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PMID: 6385935 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effect of topical timolol maleate on exercise performance was investigated in a randomized double-blind study. Healthy young subjects underwent two graded maximal exercise evaluations on a treadmill. The evaluations were given one week apart. Before each trial, the subjects were given a single drop of either placebo or 0.5% timolol maleate in each eye. The results indicate that topical timolol has a statistically significant effect on both maximal heart rate and time to exhaustion. However, we found that the drug had no effect on the physiologic parameters of Vo2, respiratory rate, Vco2, or respiratory quotient. |
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Authors:
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W J Doyle; P A Weber; R H Meeks |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Archives of ophthalmology Volume: 102 ISSN: 0003-9950 ISO Abbreviation: Arch. Ophthalmol. Publication Date: 1984 Oct |
Date Detail:
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Created Date: 1984-11-01 Completed Date: 1984-11-01 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 7706534 Medline TA: Arch Ophthalmol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1517-8 Citation Subset: AIM; IM; S |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Topical Adult Clinical Trials as Topic Double-Blind Method Exercise Test Eye Female Heart Rate / drug effects Humans Male Physical Exertion / drug effects* Placebos Random Allocation Respiration / drug effects Timolol / administration & dosage* |
| Chemical | |
Reg. No./Substance:
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0/Placebos; 26839-75-8/Timolol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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