Document Detail

Effect of topical atropine on intraocular pressure and pupil diameter in the normal horse eye.
MedLine Citation:
PMID:  11397268     Owner:  NLM     Status:  Publisher    
The objective was to determine whether topically administered 1% atropine would alter intraocular pressure. The animals studied were four healthy adult horses. Intraocular pressure and pupil diameter were measured prior to and during a 2-day period of treatment with 1% atropine sulfate. No significant changes in intraocular pressure occurred as a result of the treatment with atropine. Pupil diameter increased significantly after atropine was applied. Available information on the outflow of aqueous humor from the horse eye suggests that atropine might reduce intraocular pressure in the horse by increasing uveoscleral outflow. This could prove beneficial in the treatment of equine glaucoma. We could not confirm a significant pressure-lowering effect of atropine. It is possible, however, that a longer treatment period may be required or that atropine may have a more profound effect on glaucomatous globes.
Albert J. Mughannam; Nedim C. Buyukmihci; Philip H. Kass
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Publication Detail:
Journal Detail:
Title:  Veterinary ophthalmology     Volume:  2     ISSN:  1463-5224     ISO Abbreviation:  Vet Ophthalmol     Publication Date:  1999  
Date Detail:
Created Date:  2001-Jun-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100887377     Medline TA:  Vet Ophthalmol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  213-215     Citation Subset:  -    
Veterinary Medical Teaching Hospital; Departments of Surgical and Radiological Sciences; Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, CA 95616, USA.
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