Document Detail

Effect of topical application of coenzyme Q10 on adult periodontitis.
MedLine Citation:
PMID:  7752836     Owner:  NLM     Status:  MEDLINE    
Topical application of Coenzyme Q10 (CoQ10) to the periodontal pocket was evaluated with and without subgingival mechanical debridement. Ten male patients with adult periodontitis participated and 30 periodontal pockets were selected. During the first 3 weeks, the patients did not receive any periodontal therapy except the topical application of CoQ10. After the first 3-week period, root planning and subgingival scaling were performed in all sites. CoQ10 was applied in 20 of the pockets once a week for a period of 6 weeks. Soybean oil was applied to the remaining 10 sites as a control. In the first 3-week period, significant reductions in gingival crevicular fluid flow, probing depth and attachment loss were found only at experimental sites. After mechanical subgingival debridement, significant decreases in the plaque index, gingival crevicular fluid flow, probing depth and attachment loss were found both at experimental and control sites. However, significant improvements in the modified gingival index, bleeding on probing and peptidase activity derived from periodontopathic bacteria were observed only at experimental sites. These results suggest that topical application of CoQ10 improves adult periodontitis not only as a sole treatment but also in combination with traditional nonsurgical periodontal therapy.
T Hanioka; M Tanaka; M Ojima; S Shizukuishi; K Folkers
Related Documents :
14508666 - Protective effect of a vegetable extract from lupinus albus (lu 105) on human gingival ...
9524456 - Glass ionomer materials as a rechargeable fluoride-release system.
16114626 - Evaluation of denitrification potential of rotating biological contactors for treatment...
23351966 - Genetic determinants of voluntary exercise.
18388406 - Inter-modal comparisons of acute energy expenditure during perceptually based exercise ...
2347316 - The effect of exercise intensity and duration on the oxygen deficit and excess post-exe...
Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Molecular aspects of medicine     Volume:  15 Suppl     ISSN:  0098-2997     ISO Abbreviation:  Mol. Aspects Med.     Publication Date:  1994  
Date Detail:
Created Date:  1995-06-21     Completed Date:  1995-06-21     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7603128     Medline TA:  Mol Aspects Med     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  s241-8     Citation Subset:  IM    
Department of Preventive Dentistry, Osaka University Faculty of Dentistry, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Administration, Topical
Bacteria / isolation & purification
Combined Modality Therapy
Dental Plaque Index
Dental Scaling
Middle Aged
Periodontal Index
Periodontitis / drug therapy*,  microbiology,  therapy
Pilot Projects
Root Planing
Treatment Outcome
Ubiquinone / administration & dosage,  analogs & derivatives*,  therapeutic use
Reg. No./Substance:
0/Coenzymes; 1339-63-5/Ubiquinone; 303-98-0/coenzyme Q10

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Apparent partial remission of breast cancer in 'high risk' patients supplemented with nutritional an...
Next Document:  Coenzyme Q10 levels in human seminal fluid: diagnostic and clinical implications.