| Effect of topical anaesthesia on corneal epithelial fragility. | |
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MedLine Citation:
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PMID: 6480223 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effect of topical anaesthetics on human corneal integrity was assessed by measurement of the alterations they cause in corneal damage threshold. The anaesthetics investigated were 1.0% Amethocaine HCl, assessed immediately after instillation and after delays of 20 min and 60 min, and 0.5% Amethocaine HCl and 0.4% Benoxinate HCl, assessed 20 min after instillation. At 20 min after instillation of 1.0% Amethocaine HCl, the corneal damage threshold was significantly decreased. At other times for this anaesthetic, and for 0.5% Amethocaine HCl and 0.4% Benoxinate HCl, the corneal damage threshold was unaltered. |
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Authors:
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L G Carney; D J O'Leary; M Millodot |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: International ophthalmology Volume: 7 ISSN: 0165-5701 ISO Abbreviation: Int Ophthalmol Publication Date: 1984 Jun |
Date Detail:
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Created Date: 1984-11-21 Completed Date: 1984-11-21 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7904294 Medline TA: Int Ophthalmol Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 71-3 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anesthetics, Local
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toxicity* Cornea / drug effects* Epithelium / drug effects Humans Procaine / analogs & derivatives*, toxicity Tetracaine / toxicity* Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Anesthetics, Local; 59-46-1/Procaine; 94-24-6/Tetracaine; 99-43-4/benoxinate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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