Document Detail

Effect of tonsillectomy on the level of exhaled nitric oxide (NO) in patients with recurrent tonsillitis.
MedLine Citation:
PMID:  20729049     Owner:  NLM     Status:  In-Process    
BACKGROUND: Increased expression of inducible nitric oxide synthase in inflamed tonsils has been reported. Our preliminary observation was the first to demonstrate that increased exhaled NO level may occur in patients with tonsillitis.
OBJECTIVE: To extend the observation scope, the same group of patients was examined for NO exhaled after tonsillectomy.
MATERIALS AND METHODS: Exhaled oral NO level was measured with Niox Mino(®) analyzer, six-seven months after tonsillectomy in 27 non-atopic patients who suffered from recurrent tonsillitis and in 35 healthy non-atopic subjects.
RESULTS: After tonsillectomy, exhaled NO levels were significantly reduced as compared to the preoperative period values and did not differ significantly from those of the healthy subjects.
CONCLUSIONS: The results support a finding of the elevated exhaled NO consequent to NO production in chronically inflamed tonsils, but whether NO plays any role in the pathogenesis of tonsillitis or is merely a by-product of another process, needs to be determined.
A Kasperska-Zajac; E Czecior; G Namyslowski
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Publication Detail:
Type:  Journal Article     Date:  2010-08-21
Journal Detail:
Title:  Respiratory medicine     Volume:  104     ISSN:  1532-3064     ISO Abbreviation:  Respir Med     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-09-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8908438     Medline TA:  Respir Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  1757-9     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ltd. All rights reserved.
Chair and Clinical Department of Internal Diseases, Allergology and Clinical Immunology, Medical University of Silesia, Katowice, Poland.
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