Document Detail


Effect of time to surgical evaluation on the outcomes of infants with gastroschisis.
MedLine Citation:
PMID:  22703778     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: Our goal is to identify the impact of time to surgical intervention on the outcomes of infants with gastroschisis.
METHODS: After institutional review board approval, we performed a retrospective review of the medical records of all infants admitted to our institution from 2001 to 2010. Transport, bowel stabilization, and closure times were defined as the time from birth to admission, admission to the first-documented operative intervention, and first operative intervention to abdominal closure, respectively. Outcomes included age at full enteral feeds, total parental nutrition days, ventilator days, and hospital length of stay. Multivariate analysis was used to identify independent predictors of the outcomes.
RESULTS: One hundred eighteen infants with gastroschisis were included in our study. Transport and bowel stabilization times were not predictive of any outcome. However, the time to abdominal wall closure and postnatal gastrointestinal complications were independently predictive of age at full enteral feeds, total parenteral nutrition days, and hospital length of stay.
CONCLUSION: Time to surgical evaluation/bowel stabilization was not predictive of any clinically relevant outcomes in infants with gastroschisis. These data demonstrate that potential benefits from prenatal regionalization of infants with gastroschisis are not supported by decreased time to operative intervention.
Authors:
Brian T Bucher; Ioanna G Mazotas; Brad W Warner; Jacqueline M Saito
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of pediatric surgery     Volume:  47     ISSN:  1531-5037     ISO Abbreviation:  J. Pediatr. Surg.     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-06-18     Completed Date:  2012-10-29     Revised Date:  2013-07-12    
Medline Journal Info:
Nlm Unique ID:  0052631     Medline TA:  J Pediatr Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1105-10     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Affiliation:
Division of Pediatric Surgery, Department of Surgery, St Louis Children's Hospital, Washington University School of Medicine, St Louis, MO 63110, USA. bucherb@wudosis.wustl.edu
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Multiple / epidemiology
Enteral Nutrition / statistics & numerical data
Female
Gastroschisis / surgery*
Gestational Age
Humans
Infant, Newborn
Length of Stay / statistics & numerical data
Male
Parenteral Nutrition, Total / statistics & numerical data
Patient Transfer
Postoperative Complications / epidemiology
Pregnancy
Pregnancy Complications / epidemiology
Respiration, Artificial / statistics & numerical data
Retrospective Studies
Risk Factors
Time Factors
Treatment Outcome
Grant Support
ID/Acronym/Agency:
UL1 TR000448/TR/NCATS NIH HHS
Comments/Corrections

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