Document Detail

Effect of time interval between food intake and exercise on substrate oxidation during exercise in obese and lean children.
MedLine Citation:
PMID:  21696868     Owner:  NLM     Status:  Publisher    
BACKGROUND & AIMS: Exercise induces adaptations in fat metabolism favourable to the treatment of obesity. However, time interval between meal and exercise alters substrate bioavailability and oxidation during exercise. The aim of this study was therefore to investigate the effect of time interval between food intake and exercise on substrate oxidation rates in obese and lean children. METHODS: The metabolic responses to exercise of nine obese children (10.3 ± 1.8 years; %body fat: 36.1 ± 6.1) and seven lean children (9.2 ± 1.6 years; %body fat: 22.2 ± 4.1) were compared 1 h (time interval 1, TI1) and 3 h (TI3) after a standardized breakfast. RESULTS: Despite significantly lower plasma glucose and insulin concentrations and large effect size suggesting a higher plasma FFA availability (lean, 1.43, obese 0.98), fat oxidation was not significantly increased in TI3 compared to TI1 in both lean and obese children. Fat oxidation contributed marginally to energy expenditure during exercise (<20%) in both conditions and groups but was moderately increased during TI3 compared to TI1 in lean children (effect size: 0.54). CONCLUSIONS: The low contribution of fat oxidation to energy expenditure during exercise in obese and lean children fed 3 h before exercise questions the efficacy of moderate intensity exercise to favourably affect fat balance.
Julien Aucouturier; Laurie Isacco; David Thivel; Nicole Fellmann; Jean-Michel Chardigny; Martine Duclos; Pascale Duché
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-6-21
Journal Detail:
Title:  Clinical nutrition (Edinburgh, Scotland)     Volume:  -     ISSN:  1532-1983     ISO Abbreviation:  -     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-6-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8309603     Medline TA:  Clin Nutr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.
Laboratoire Universitaire de Biologie des Activités Physiques et Sportives (BAPS), Université Blaise Pascal, Clermont-Ferrand, Batiment de Biologie B, Campus Universitaire des Cézeaux, 63177 Aubière Cedex, France; Université Droit et Santé Lille 2, EA 4488 "Activité Physique, Muscle, Santé", Faculté des Sciences du Sport et de l'Education Physique, 59790 Ronchin, France.
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