Document Detail

Effect of thin femtosecond LASIK flaps on corneal sensitivity and tear function.
MedLine Citation:
PMID:  19044230     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To evaluate changes in comeal sensitivity and tear function following myopic LASIK with thin femtosecond flaps. METHODS: A retrospective study was performed to compare corneal sensitivity (filament), tear breakup time, and anesthetized Schirmer test preoperatively and at 1 week and 2 and 6 months postoperatively. RESULTS: Seventy-two eyes of 38 consecutive patients (20 women and 18 men) who underwent LASIK for myopia or myopic astigmatism with thin femtosecond flaps (IntraLase femtosecond laser system and Technolas 217 PlanoScan V2.9992 or wavefront-guided Zyoptix 3.1 excimer laser) were evaluated. Preoperative mean corneal sensitivity was 5.3+/-1.5 mm, which decreased to 4.6+/-1.7 mm at 1 week, increased to 5.0+/-1.3 mm at 2 months, and returned to baseline values at 6 months postoperatively. Mean Schirmer score was 13.7+/-5.7 mm preoperatively and 12.1+/-5.1, 13.1+/-4.8, and 13.0+/-5.1 mm at 1 week and 2 and 6 months postoperatively, respectively. Mean tear breakup time was 7.7+/-2.6 seconds preoperatively and 7.8+/-3.5, 9.2+/-4.6, and 8.8+/-4.5 seconds at 1 week and 2 and 6 months postoperatively, respectively. No significant increase in fluorescein staining was observed throughout follow-up. CONCLUSIONS: Reductions in corneal sensitivity and tear function tests were minimal after myopic LASIK with thin femtosecond flaps. Despite the relatively narrow hinge, the thin, uniform femtosecond flap does not appear to have an adverse effect on corneal sensitivity and dry eye signs at 6 months postoperatively.
Irina S Barequet; Ami Hirsh; Samuel Levinger
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of refractive surgery (Thorofare, N.J. : 1995)     Volume:  24     ISSN:  1081-597X     ISO Abbreviation:  J Refract Surg     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2008-12-02     Completed Date:  2009-01-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9505927     Medline TA:  J Refract Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  897-902     Citation Subset:  IM    
Enaim Refractive Surgery Centers, Tel Aviv, Israel.
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MeSH Terms
Astigmatism / surgery*
Cornea / physiology*
Corneal Stroma / pathology
Corneal Topography
Keratomileusis, Laser In Situ*
Lasers, Excimer / therapeutic use*
Middle Aged
Myopia / surgery*
Retrospective Studies
Surgical Flaps / pathology*
Tears / physiology*
Visual Acuity / physiology
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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