Document Detail

Effect of theophylline on the riboflavin-sensitized photodegradation of bilirubin in vitro.
MedLine Citation:
PMID:  7388087     Owner:  NLM     Status:  MEDLINE    
Under in vitro conditions, theophylline accelerates the rate of bilirubin photodestuction sensitized by riboflavin, but does not do so in absence of this dye. The effect depends on the concentrations of theophylline and/or riboflavin, on the bilirubin/albumin ratio, and seems to implicate bilirubin unbound to serum albumin. Possible causes of the theophylline action and clinical implication regarding thephototherapy of neonatal jaundice are discussed.
P Meisel; I Amon; H Hüller; K Jährig
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biology of the neonate     Volume:  38     ISSN:  0006-3126     ISO Abbreviation:  Biol. Neonate     Publication Date:  1980  
Date Detail:
Created Date:  1980-09-26     Completed Date:  1980-09-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0247551     Medline TA:  Biol Neonate     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  30-5     Citation Subset:  IM    
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MeSH Terms
Bilirubin / radiation effects*
Infant, Newborn
Jaundice, Neonatal / therapy
Riboflavin / pharmacology*
Serum Albumin / analysis
Theophylline / pharmacology*
Reg. No./Substance:
0/Serum Albumin; 58-55-9/Theophylline; 635-65-4/Bilirubin; 83-88-5/Riboflavin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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