Document Detail


Effect of tea (Camellia sinensis L.) on lipid peroxidation in rat liver and kidney: a comparison of green and black tea feeding.
MedLine Citation:
PMID:  7581239     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The antioxidant effects in the liver and kidney obtained from rat fed diets containing 3% green or black tea leaf powder, which were prepared from the same lot tea leaves, were studied using the tissue slice-antioxidant evaluation method with two lipid peroxidation inducers. After 50 d on the diets, liver slices prepared from green and black tea-supplemented rats showed significant inhibitory effects against tert-butyl hydroperoxide-induced lipid peroxidation. These effects, however, were not proportional to the amounts of (-)-epicatechins and antioxidant vitamins in the tea leaves. In the kidney, the antioxidant effect was observed only in the green tea-fed group. A similar antioxidant effect on the kidney was observed after oral administration of a major tea polyphenol, (-)-epigallocatechin gallate (50 mg/kg body weight for 7 d). Liver slices from black tea-fed rats also inhibited bromotrichloromethane-induced lipid peroxidation. These results demonstrated that dietary green and black tea had antioxidant effects on tissue lipid peroxidation ex vivo.
Authors:
M Sano; Y Takahashi; K Yoshino; K Shimoi; Y Nakamura; I Tomita; I Oguni; H Konomoto
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biological & pharmaceutical bulletin     Volume:  18     ISSN:  0918-6158     ISO Abbreviation:  Biol. Pharm. Bull.     Publication Date:  1995 Jul 
Date Detail:
Created Date:  1995-12-08     Completed Date:  1995-12-08     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9311984     Medline TA:  Biol Pharm Bull     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  1006-8     Citation Subset:  IM    
Affiliation:
Laboratory of Health Science, School of Pharmaceutical Sciences, University of Shizuoka, Japan.
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MeSH Terms
Descriptor/Qualifier:
Animals
Antioxidants / pharmacology*
Body Weight / drug effects
Eating / drug effects
Electrocardiography / drug effects
Kidney / drug effects,  metabolism*
Lipid Peroxidation / drug effects*
Liver / drug effects,  metabolism*
Male
Plant Extracts / pharmacology
Rats
Rats, Wistar
Tea* / chemistry*
Thiobarbituric Acid Reactive Substances / metabolism
Vitamin E / metabolism
Chemical
Reg. No./Substance:
0/Antioxidants; 0/Plant Extracts; 0/Tea; 0/Thiobarbituric Acid Reactive Substances; 1406-18-4/Vitamin E

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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